Article
Serum ferritin level predicts advanced hepatic fibrosis among U.S. patients with phenotypic hemochromatosis.
Annals of internal medicine - 15 Apr 2003
Morrison Elizabeth D, Brandhagen David J, Phatak Pradyumna D, Barton James C, Krawitt Edward L, El-Serag Hashem B, Gordon Stuart C, Galan Mark V, Tung Bruce Y, Ioannou George N, Kowdley Kris V
Abstract excerpt
BACKGROUND: DNA-based HFE gene testing can confirm hereditary hemochromatosis in most people of Northern European descent. However, liver biopsy is important to detect cirrhosis. OBJECTIVE: To develop noninvasive criteria to predict the presence or absence of advanced hepatic fibrosis or cirrhosis in Americans with hemochromatosis. DESIGN: Cross-sectional study. SETTING: Six tertiary care referral clinics....
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