Article
Absence of Bruton's tyrosine kinase (Btk) mutations in patients with acute myeloid leukaemia.
British journal of haematology - 1 Sept 1998
Ritis K, Speletas M, Tsironidou V, Pardali E, Kanariou M, Moschese V, Orlandi P, Skordala M, Rossi P, Kartalis G, Bourikas G, Sideras P
Abstract excerpt
Bruton's tyrosine kinase (Btk) is a non-receptor protein tyrosine kinase (PTK) that is expressed in all haemopoietic lineages except mature T cells and plasma cells. Despite the broad range of expression. mutations that inactivate this molecule affect primarily the development of the B-cell lineage. As a PTK, Btk could potentially be involved directly or indirectly in the processes that relate to the malignant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.