[Paroxysmal nocturnal hemoglobinuria and its association with aplastic anemia].

Article

[Paroxysmal nocturnal hemoglobinuria and its association with aplastic anemia].

Casopis lekaru ceskych - 13 Jul 1998

Pavlů J, Necas E

Abstract excerpt

Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired clonal disorder of haematopoiesis. Clinically it is characterized by intravascular haemolysis, venous thrombosis and often by bone marrow hypoplasia. Haemolysis and thrombosis develop as a consequence of deficiency of several proteins on t...

Topics

Anemia, Aplastic
Hemoglobinuria, Paroxysmal
Humans
Mutation

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