Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Paroxysmal nocturnal hemoglobinuria and its association with aplastic anemia].

Casopis lekaru ceskych - 13 Jul 1998

Pavlů J, Necas E

Abstract excerpt

Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired clonal disorder of haematopoiesis. Clinically it is characterized by intravascular haemolysis, venous thrombosis and often by bone marrow hypoplasia. Haemolysis and thrombosis develop as a consequence of deficiency of several proteins on the cell membrane of the affected clone of blood elements. This is caused by somatic mutations in the PIG-A gene, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Aplastic
Share to GPI gene
Share to Hemoglobinuria, Paroxysmal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Source

Identifiers

PMID: 9748736

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Paroxysmal nocturnal hemoglobinuria and its association with aplastic anemia].PMID 9748736Read ↗

[Paroxysmal nocturnal hemoglobinuria].Semantic proximity Read ↗

Recent advances in paroxysmal nocturnal hemoglobinuria. From the biology to the clinic.Semantic proximity Read ↗

PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesis.Semantic proximity Read ↗

Paroxysmal nocturnal hemoglobinuria: An acquired genetic disease.Semantic proximity Read ↗

Paroxysmal nocturnal hemoglobinuria in children.Semantic proximity Read ↗

PIG-A gene mutations in four Taiwanese patients with paroxysmal nocturnal haemoglobinuria following aplastic anaemia.Semantic proximity Read ↗

The molecular basis of paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

[Paroxysmal nocturnal hemoglobinuria (PNH)].Semantic proximity Read ↗

Paroxysmal Nocturnal Hemoglobinuria as a Molecular DiseaseSemantic proximity Read ↗

Recent insights into the pathophysiology of paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Molecular genetics of paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Paroxysmal nocturnal hemoglobinuria: insights from recent advances in molecular biology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.