Ndd, the bacteriophage T4 protein that disrupts the Escherichia coli nucleoid, has a DNA binding activity.

doi:10.1128/JB.180.19.5227-5230.1998

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Article

Ndd, the bacteriophage T4 protein that disrupts the Escherichia coli nucleoid, has a DNA binding activity.

Journal of bacteriology - 1 Oct 1998

Bouet J Y, Krisch H M, Louarn J M

Abstract excerpt

Early in a bacteriophage T4 infection, the phage ndd gene causes the rapid destruction of the structure of the Escherichia coli nucleoid. Even at very low levels, the Ndd protein is extremely toxic to cells. In uninfected E. coli, overexpression of the cloned ndd gene induces disruption of the nu...

Topics

Bacteriophage T4
DNA, Bacterial
DNA, Viral
Escherichia coli
Mutation
Protein Binding
Temperature
Viral Proteins

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