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Article

Viral terminal protein directs early organization of phage DNA replication at the bacterial nucleoid.

Proceedings of the National Academy of Sciences of the United States of America - 21 Sept 2010

Muñoz-Espín Daniel, Holguera Isabel, Ballesteros-Plaza David, Carballido-López Rut, Salas Margarita

Abstract excerpt

The mechanism leading to protein-primed DNA replication has been studied extensively in vitro. However, little is known about the in vivo organization of the proteins involved in this fundamental process. Here we show that the terminal proteins (TPs) of phages ϕ29 and PRD1, infecting the distantly related bacteria Bacillus subtilis and Escherichia coli, respectively, associate with the host bacterial nucleoid...

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Source

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Identifiers

PMID: 20823229
DOI: 10.1073/pnas.1010530107
PMCID: PMC2944753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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