A 45 bp inverted repeat is required for cell cycle regulation of the Escherichia coli nrd operon.

doi:10.1046/j.1365-2958.1998.00896.x

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Article

A 45 bp inverted repeat is required for cell cycle regulation of the Escherichia coli nrd operon.

Molecular microbiology - 1 Jun 1998

Jacobson B A, Fuchs J A

Abstract excerpt

Expression of beta-galactosidase from a nrd-lacZ fusion was used to determine the role in nrd regulation of an inverted sequence upstream of the promoter. Removal or replacement of a 45bp inverted repeat with an altered sequence including a 48bp perfect inverted repeat resulted in a mutant phenot...

Topics

Artificial Gene Fusion
Cell Cycle
DNA Replication
Escherichia coli
Gene Expression Regulation, Bacterial
Lac Operon
Mutation
Operon
Plasmids
Promoter Regions, Genetic
Repetitive Sequences, Nucleic Acid
Ribonucleotide Reductases
Thymine
Time Factors
beta-Galactosidase

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