Article
The role of caspases in photoreceptor cell death of the retinoschisin-deficient mouse.
Cytogenetic and genome research - 1 Jan 2006
Gehrig A, Janssen A, Horling F, Grimm C, Weber B H F
Abstract excerpt
Early schisis cavities in the retinal bipolar cell layer accompanied by progressive loss of cone and rod photoreceptor cells are the hallmark of the retinoschisin-deficient (Rs1h(-/Y)) murine retina. With this study we aimed at elucidating the molecular events underlying the photoreceptor cell death in this established murine model of X-linked juvenile retinoschisis. We show that photoreceptor degeneration in the...
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