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Article

Defects in protein glycosylation cause SHO1-dependent activation of a STE12 signaling pathway in yeast.

Genetics - 1 Jul 2000

Cullen P J, Schultz J, Horecka J, Stevenson B J, Jigami Y, Sprague G F

Abstract excerpt

In haploid Saccharomyces cerevisiae, mating occurs by activation of the pheromone response pathway. A genetic selection for mutants that activate this pathway uncovered a class of mutants defective in cell wall integrity. Partial loss-of-function alleles of PGI1, PMI40, PSA1, DPM1, ALG1, MNN10, SPT14, and OCH1, genes required for mannose utilization and protein glycosylation, activated a...

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Share to Genetic Complementation Test
Share to Glycosylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mannose

Share to Membrane Glycoproteins

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Source

Open in PubMed Open full text

Identifiers

PMID: 10880465
DOI: 10.1093/genetics/155.3.1005
PMCID: PMC1461155

Genes

ALG1
DPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Defects in protein glycosylation cause SHO1-dependent activation of a STE12 signaling pathway in yeast.PMID 10880465Read ↗

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