Article
Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila.
Development (Cambridge, England) - 1 Oct 1998
Haerry T E, Khalsa O, O'Connor M B, Wharton K A
Abstract excerpt
In Drosophila wing discs, a morphogen gradient of DPP has been proposed to determine the transcriptional response thresholds of the downstream genes sal and omb. We present evidence that the concentration of the type I receptor TKV must be low to allow long-range DPP diffusion. Low TKV receptor c...
Topics
- Animals
- Body Patterning
- DNA-Binding Proteins
- Diffusion
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression Regulation, Developmental
- Genes, Insect
- Immunohistochemistry
- In Situ Hybridization
- Insect Proteins
- Models, Biological
- Nerve Tissue Proteins
- Phenotype
- Protein Serine-Threonine Kinases