Article
Increased MAPK activity and MKP-1 overexpression in human gastric adenocarcinoma.
Biochemical and biophysical research communications - 8 Sept 1998
Bang Y J, Kwon J H, Kang S H, Kim J W, Yang Y C
Abstract excerpt
Mitogen-activated protein kinase (MAPK) has been known to play a critical role in the regulation of the carcinogenesis in human cancers. In an effort to understand the functional role of the MAPK in the carcinogenesis of human gastric tissues, we examined the changes of MAPK levels in human gastr...
Topics
- Adenocarcinoma
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Cycle Proteins
- Dual Specificity Phosphatase 1
- Enzyme Inhibitors
- Gastric Mucosa
- Genes, ras
- Humans
- Immediate-Early Proteins
- Mutation
- Phosphoprotein Phosphatases
- Phosphorylation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Protein Phosphatase 1
- Protein Tyrosine Phosphatases
- Stomach Neoplasms