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Article

Mitogen-activated protein kinase signal transduction in solid tumors.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Lei Yuan-Yuan, Wang Wei-Jia, Mei Jin-Hong, Wang Chun-Liang

Abstract excerpt

Mitogen-activated protein kinase (MAPK) is an important signaling pathway in living beings in response to extracellular stimuli. There are 5 main subgroups manipulating by a set of sequential actions: ERK(ERK1/ ERK2), c-Jun N(JNK/SAPK), p38 MAPK(p38α, p38β, p38γ and p38δ), and ERK3/ ERK4/ ERK5. When stimulated, factors of upstream or downstream change, and by interacting with each other, these groups have long...

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Identifiers

PMID: 25374165
DOI: 10.7314/apjcp.2014.15.20.8539

Genes

DUSP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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