In vivo selection of Rous sarcoma virus mutants with randomized sequences in the packaging signal.

doi:10.1128/JVI.72.10.8073-8082.1998

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Article

In vivo selection of Rous sarcoma virus mutants with randomized sequences in the packaging signal.

Journal of virology - 1 Oct 1998

Doria-Rose N A, Vogt V M

Abstract excerpt

Retrovirus genomes contain a sequence at the 5' end which directs their packaging into virions. In Rous sarcoma virus, previous studies have identified important segments of the packaging signal, Psi, and support elements of a secondary-structure prediction. To further characterize this sequence,...

Topics

Avian Sarcoma Viruses
Base Sequence
Cells, Cultured
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
RNA, Viral
Selection, Genetic
Turkey
Virus Assembly

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