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Article

Interactive effect of PAI-1 4G/5G genotype and salt intake on PAI-1 antigen.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2001

Brown N J, Murphey L J, Srikuma N, Koschachuhanan N, Williams G H, Vaughan D E

Abstract excerpt

Activation of the renin-angiotensin-aldosterone system (RAAS) is associated with increased circulating PAI-1 antigen and increased risk of thrombotic cardiovascular events. A 4G/5G polymorphism located 675 bp upstream from the transcription start site of the PAI-1 gene affects PAI-1 antigen concentrations. To test the hypothesis that PAI-1 4G/5G genotype influences the effect of activation of the RAAS on PAI-1...

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Source

Identifiers

PMID: 11397722
DOI: 10.1161/01.atv.21.6.1071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interactive effect of PAI-1 4G/5G genotype and salt intake on PAI-1 antigen.PMID 11397722Read ↗

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