Article
Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants.
The Biochemical journal - 15 Sept 1998
Tiede A, Schubert J, Nischan C, Jensen I, Westfall B, Taron C H, Orlean P, Schmidt R E
Abstract excerpt
Glycosylphosphatidylinositol (GPI) represents an important anchoring molecule for cell surface proteins. The first step in its synthesis is the transfer of N-acetylglucosamine (GlcNAc) from UDP to phosphatidylinositol (PI). The products of three mammalian genes, PIG-A, PIG-C and PIG-H, have previ...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Membrane
- Cloning, Molecular
- DNA Primers
- Fungal Proteins
- Gene Expression
- Glycosylphosphatidylinositols
- Humans
- Membrane Proteins
- Mice
