A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis.

Article

A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis.

The Journal of biological chemistry - 8 Apr 1994

Leidich S D, Drapp D A, Orlean P

Abstract excerpt

Glycosyl phosphatidylinositols (GPIs) anchor many proteins to the surface of eukaryotic cells and may also serve as sorting signals on proteins and participate in signal transduction. We have isolated a Saccharomyces cerevisiae GPI anchoring mutant, gpi1, using a colony screen for cells blocked i...

Topics

Carbohydrate Sequence
Crosses, Genetic
Genes, Fungal
Genes, Lethal
Glycosylphosphatidylinositols
Molecular Sequence Data
Mutation
Saccharomyces cerevisiae

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