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Article

Impaired growth of an Escherichia coli rpe mutant lacking ribulose-5-phosphate epimerase activity.

Biochimica et biophysica acta - 24 Aug 1998

Lyngstadaas A, Sprenger G A, Boye E

Abstract excerpt

We present evidence that ribulose-5-phosphate epimerase, a central metabolic enzyme acting in the non-oxidative branch of the pentose-phosphate pathway, is encoded by a gene in the dam containing operon of Escherichia coli. Enzymatic assays confirm that this gene encodes ribulose-5-phosphate epimerase activity. Disruption of the gene (rpe) causes loss of enzymatic activity and renders the rpe mutant unable to...

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PMID: 9729441
DOI: 10.1016/s0304-4165(98)00046-4

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