Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of the putative effector region of Era, an essential GTP-binding protein in Escherichia coli, causes a dominant-negative phenotype.

FEMS microbiology letters - 15 Sept 1996

Pillutla R C, Ahnn J, Inouye M

Abstract excerpt

Era is an essential gene in E. coli, encoding a GTP-binding protein of unknown function. In the present work, a mutant designated Era-dE, for deletion of effector region is described. This is the first and only known era allele that confers a dominant-negative phenotype. Phenotypic analysis of the mutant showed that overproduction of Era-dE caused a dominant inhibition of growth when TCA cycle intermediates such...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Bacterial
Share to Bacterial Proteins
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli Proteins

Share to Gene Deletion

Share to GTP-Binding Proteins

Share to Mutation

Share to Phenotype

Source

Identifiers

PMID: 8807801
DOI: 10.1111/j.1574-6968.1996.tb08460.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of the putative effector region of Era, an essential GTP-binding protein in Escherichia coli, causes a dominant-negative phenotype.PMID 8807801Read ↗

Pleiotropic changes resulting from depletion of Era, an essential GTP-binding protein in Escherichia coli.Semantic proximity Read ↗

Mutational analysis of Era, an essential GTP-binding protein of Escherichia coli.Semantic proximity Read ↗

The widely conserved Era G-protein contains an RNA-binding domain required for Era function in vivo.Semantic proximity Read ↗

Cell cycle arrest in Era GTPase mutants: a potential growth rate-regulated checkpoint in Escherichia coli.Semantic proximity Read ↗

Cross-species complementation of the indispensable Escherichia coli era gene highlights amino acid regions essential for activity.Semantic proximity Read ↗

MazG, a nucleoside triphosphate pyrophosphohydrolase, interacts with Era, an essential GTPase in Escherichia coli.Semantic proximity Read ↗

A Francisella tularensis DNA clone complements Escherichia coli defective for the production of Era, an essential Ras-like GTP-binding protein.Semantic proximity Read ↗

Characterization of mutations affecting the Escherichia coli essential GTPase era that suppress two temperature-sensitive dnaG alleles.Semantic proximity Read ↗

Cold-sensitive growth and decreased GTP-hydrolytic activity from substitution of Pro17 for Val in Era, an essential Escherichia coli GTPase.Semantic proximity Read ↗

Up-regulation of yggG promotes the survival of Escherichia coli cells containing Era-1 mutant protein.Semantic proximity Read ↗

Suppression of defective ribosome assembly in a rbfA deletion mutant by overexpression of Era, an essential GTPase in Escherichia coli.Semantic proximity Read ↗

GTP-binding protein Era: a novel gene target for biofuel production.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.