Article
Emergence of an S gene mutant during thymosin alpha1 therapy in a patient with chronic hepatitis B.
The Journal of infectious diseases - 1 Sept 1998
Tang J H, Yeh C T, Chen T C, Hsieh S Y, Chu C M, Liaw Y F
Abstract excerpt
The presence of a hepatitis B virus S gene mutant was investigated in a patient being treated with thymosin alpha1. He was seropositive for hepatitis B e antigen throughout therapy but was intermittently seronegative for hepatitis B surface antigen (HBsAg) by an RIA. Sequence analysis revealed an...
Topics
- Adult
- Amino Acid Sequence
- Antiviral Agents
- Genes, Viral
- Hepatitis B Surface Antigens
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Thymalfasin
- Thymosin