Article
Study of the frequencies of CYP1A1 gene polymorphisms and glutathione S-transferase mu1 gene in primary breast cancers: an update with an additional 114 cases.
Mutation research - 17 Jul 1998
Fontana X, Peyrottes I, Rossi C, Leblanc-Talent P, Ettore F, Namer M, Bussière F
Abstract excerpt
We studied the polymorphisms m1 (Msp1 restriction site) and m2 (codon Val substitution) of CYP1A1 gene and the copy number of glutathione S-transferase mu1 (GSTM1) gene on 487 DNA of breast cancer primary tumours from Caucasian group. Tumours of patients aged 55 years and under at diagnosis prese...
Topics
- Adult
- Aged
- Aged, 80 and over
- Breast Neoplasms
- Cathepsin D
- Cytochrome P-450 CYP1A1
- DNA, Neoplasm
- Deoxyribonuclease HpaII
- Female
- Gene Amplification
- Genotype
- Glutathione Transferase
- Humans
- Middle Aged
- Point Mutation
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Prognosis
