[Glutathione S-transferase mu 1 (GSTM1): susceptibility gene of breast cancer].

Article

[Glutathione S-transferase mu 1 (GSTM1): susceptibility gene of breast cancer].

Bulletin du cancer - 1 Jan 1997

Fontana X, Peyrotte I, Valente E, Rossi C, Ettore F, Namer M, Bussière F

Abstract excerpt

Glutathione S-transferases mu (GSTM) are dimeric cytosolic isoenzymes. They catalyze glutathione conjugation upon a large variety of electrophiles as carcinogens, trans-stilbene peroxide or benzo(a)pyrene. The gene GSTM1 is localized on chromosome 1p13, it has drawn attention because it is absent...

Topics

Adult
Age Factors
Aged
Aged, 80 and over
Breast Neoplasms
DNA
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Glutathione Transferase
Humans
Middle Aged
Polymerase Chain Reaction
Polymorphism, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.