Genetic studies of mei-1 gene activity during the transition from meiosis to mitosis in Caenorhabditis elegans.

doi:10.1093/genetics/134.1.199

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Article

Genetic studies of mei-1 gene activity during the transition from meiosis to mitosis in Caenorhabditis elegans.

Genetics - 1 May 1993

Clandinin T R, Mains P E

Abstract excerpt

Genetic evidence suggests that the mei-1 locus of Caenorhabditis elegans encodes a maternal product required for female meiosis. However, a dominant gain-of-function allele, mei-1(ct46), can support normal meiosis but causes defects in subsequent mitotic spindles. Previously identified intragenic...

Topics

Alleles
Animals
Caenorhabditis elegans
Embryonic and Fetal Development
Female
Genes, Dominant
Genes, Helminth
Genes, Suppressor
Meiosis
Mitosis
Models, Genetic
Phenotype

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