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Article

Genetic studies of mei-1 gene activity during the transition from meiosis to mitosis in Caenorhabditis elegans.

Genetics - 1 May 1993

Clandinin T R, Mains P E

Abstract excerpt

Genetic evidence suggests that the mei-1 locus of Caenorhabditis elegans encodes a maternal product required for female meiosis. However, a dominant gain-of-function allele, mei-1(ct46), can support normal meiosis but causes defects in subsequent mitotic spindles. Previously identified intragenic suppressors of ct46 lack functional mei-1 activity; null alleles suppress only in cis but other alleles arise...

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Identifiers

PMID: 8514128
DOI: 10.1093/genetics/134.1.199
PMCID: PMC1205422

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