Article
Virtues of being faithful: can we limit the genetic variation in human immunodeficiency virus?
Journal of molecular medicine (Berlin, Germany) - 1 Aug 1998
Drosopoulos W C, Rezende L F, Wainberg M A, Prasad V R
Abstract excerpt
Human immunodeficiency virus (HIV) infections are characterized by a high degree of viral variation. The genetic variation is thought to be a combined effect of a high error rate of reverse transcriptase (RT), viral genomic recombination, the selection forces of the human immune system, the requirement for growth in multiple cell types during pathogenesis, and persistent immune activation associated with HIV...
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