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Article

The optx2 homeobox gene is expressed in early precursors of the eye and activates retina-specific genes.

Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1998

Toy J, Yang J M, Leppert G S, Sundin O H

Abstract excerpt

Vertebrate eye development begins at the gastrula stage, when a region known as the eye field acquires the capacity to generate retina and lens. Optx2, a homeobox gene of the sine oculis-Six family, is selectively expressed in this early eye field and later in the lens placode and optic vesicle. The distal and ventral portion of the optic vesicle are fated to become the retina and optic nerve, whereas the dorsal...

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Identifiers

PMID: 9724757
DOI: 10.1073/pnas.95.18.10643
PMCID: PMC27948

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The optx2 homeobox gene is expressed in early precursors of the eye and activates retina-specific genes.PMID 9724757Read ↗

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Six6 (Optx2) is a novel murine Six3-related homeobox gene that demarcates the presumptive pituitary/hypothalamic axis and the ventral optic stalk.Semantic proximity Read ↗

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