Article
The optx2 homeobox gene is expressed in early precursors of the eye and activates retina-specific genes.
Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1998
Toy J, Yang J M, Leppert G S, Sundin O H
Abstract excerpt
Vertebrate eye development begins at the gastrula stage, when a region known as the eye field acquires the capacity to generate retina and lens. Optx2, a homeobox gene of the sine oculis-Six family, is selectively expressed in this early eye field and later in the lens placode and optic vesicle....
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chick Embryo
- Cloning, Molecular
- DNA, Complementary
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Homeodomain Proteins
- Molecular Sequence Data
- Phenotype
- Pigment Epithelium of Eye
- Sequence Homology, Amino Acid
- Trans-Activators