Article
Glucocorticoid receptor polymorphism in genetic hypertension.
Journal of molecular endocrinology - 1 Aug 1998
Kenyon C J, Panarelli M, Zagato L, Torielli L, Heeley R P, Holloway C D, Fraser R, Casari G, Sutcliffe R G, Bianchi G
Abstract excerpt
The Milan hypertensive strain of rat (MHS) displays abnormalities in both renal function and adrenocortical activity. While the pressor role of the former has been studied in detail, the role of the latter has not yet been clearly evaluated. In the present study, glucocorticoid receptor (GR) bind...
Topics
- Animals
- Base Sequence
- Binding, Competitive
- DNA Primers
- Dexamethasone
- Female
- Genotype
- Hypertension
- Male
- Phenotype
- Point Mutation
- Polymorphism, Genetic
- Rats
- Receptors, Glucocorticoid
- Temperature