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Article

Gain of function mutation in the mineralocorticoid receptor of the Brown Norway rat.

The Journal of biological chemistry - 17 Sept 2004

Marissal-Arvy Nathalie, Lombès Marc, Petterson Jessica, Moisan Marie-Pierre, Mormède Pierre

Abstract excerpt

The aim of this research was to identify the molecular bases of differences in sensitivity to corticosteroid hormones between Brown Norway and Fischer 344 rats. We previously showed an apparent insensitivity to adrenalectomy in Brown Norway rats. Based on our first hypothesis of a different activity/reactivity of the mineralocorticoid signaling pathway between the two rat strains, we sequenced Brown Norway and...

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PMID: 15252022
DOI: 10.1074/jbc.M407436200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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