Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of glucocorticoid receptor mutations in hypertension and adrenal gland hyperplasia.

Pflugers Archiv : European journal of physiology - 1 Aug 2022

Verouti Sophia, Hummler Edith, Vanderriele Paul-Emmanuel

Abstract excerpt

Hypertension is one of the leading causes of premature death in humans and exhibits a complex aetiology including environmental and genetic factors. Mutations within the glucocorticoid receptor (GR) can cause glucocorticoid resistance, which is characterized by several clinical features like hypercortisolism, hypokalaemia, adrenal hyperplasia and hypertension. Altered glucocorticoid receptor signalling further...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Glands
Share to Glucocorticoids
Share to Hyperplasia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension

Share to Metabolism, Inborn Errors

Share to Receptors, Glucocorticoid

Share to Receptors, Mineralocorticoid

Source

Open in PubMed Open full text

Identifiers

PMID: 35732960
DOI: 10.1007/s00424-022-02715-6
PMCID: PMC9217122

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of glucocorticoid receptor mutations in hypertension and adrenal gland hyperplasia.PMID 35732960Read ↗

Glucocorticoid and mineralocorticoid receptors and associated diseases.Semantic proximity Read ↗

GENETICS IN ENDOCRINOLOGY: Glucocorticoid resistance syndromeSemantic proximity Read ↗

Inherited forms of mineralocorticoid hypertension.Semantic proximity Read ↗

Glucocorticoid Resistance Syndrome: A Systematic Review of the Genotypes, Phenotypes, and Their Relationships.Semantic proximity Read ↗

Genetics of mineralocorticoid excess: an update for clinicians.Semantic proximity Read ↗

A NOVEL GLUCOCORTICOID RECEPTOR MUTATION IN PRIMARY GENERALIZED GLUCOCORTICOID RESISTANCE DISEASE.Semantic proximity Read ↗

Generalized glucocorticoid resistance: clinical aspects, molecular mechanisms, and implications of a rare genetic disorder.Semantic proximity Read ↗

Pathophysiology of Glucocorticoid Signaling.Semantic proximity Read ↗

Novel causes of generalized glucocorticoid resistance.Semantic proximity Read ↗

Genetics of hypertensive syndrome.Semantic proximity Read ↗

Familial glucocorticoid receptor haploinsufficiency by non-sense mediated mRNA decay, adrenal hyperplasia and apparent mineralocorticoid excess.Semantic proximity Read ↗

Genetics of the mineralocorticoid system in primary hypertension.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.