Article
Functional interaction of Isr1, a predicted protein kinase, with the Pkc1 pathway in Saccharomyces cerevisiae.
Bioscience, biotechnology, and biochemistry - 1 Jul 1998
Miyahara K, Hirata D, Miyakawa T
Abstract excerpt
Staurosporine is a potent inhibitor of protein kinase C. To identify the genes that functionally interact with the Pkc1 pathway of the yeast Saccharomyces cerevisiae, we screened for the genes that cause induced staurosporine sensitivity when overexpressed from a galactose-inducible promoter. The...
Topics
- Culture Media
- Enzyme Inhibitors
- Fungal Proteins
- Gene Expression Regulation, Enzymologic
- Genes, Fungal
- Mitogen-Activated Protein Kinases
- Phenotype
- Protein Kinase C
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Signal Transduction
- Staurosporine