Article
Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Feb 1996
Gritti A, Parati E A, Cova L, Frolichsthal P, Galli R, Wanke E, Faravelli L, Morassutti D J, Roisen F, Nickel D D, Vescovi A L
Abstract excerpt
It has been established that the adult mouse forebrain contains multipotential (neuronal/glial) progenitor cells that can be induced to proliferate in vitro when epidermal growth factor is provided. These cells are found within the subventricular zone of the lateral ventricles, together with other progenitor cell populations, whose requirements for proliferation remain undefined. Using basic fibroblast growth...
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