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Article

Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4.

Journal of the National Cancer Institute - 19 Aug 1998

Rebbeck T R, Jaffe J M, Walker A H, Wein A J, Malkowicz S B

Abstract excerpt

BACKGROUND: Pathways involved in androgen metabolism have been implicated in the etiology of prostate cancer. The goal of this study was to evaluate the effect of CYP3A4, a gene associated with the oxidative deactivation of testosterone, on the clinical presentation of prostate cancers. METHODS: A polymerase chain reaction-based approach was used to identify sequence variants of the human CYP3A4 gene. To...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9719084
DOI: 10.1093/jnci/90.16.1225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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