Article
The human placenta and fetal membranes express the corticotropin-releasing hormone receptor 1alpha (CRH-1alpha) and the CRH-C variant receptor.
The Journal of clinical endocrinology and metabolism - 1 Apr 1998
Karteris E, Grammatopoulos D, Dai Y, Olah K B, Ghobara T B, Easton A, Hillhouse E W
Abstract excerpt
Placentally derived CRH plays a major role in the mechanisms controlling human pregnancy and parturition. It has been suggested that there is a CRH placental clock that is active from the early stages of pregnancy and determines the length of gestation and the timing of parturition. CRH can influence human reproductive tissue function via specific CRH receptors. Two distinct CRH receptors have been cloned (R1 and...
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