Article
The effects of growth hormone on adipose tissue: old observations, new mechanisms.
Nature reviews. Endocrinology - 1 Mar 2020
Kopchick John J, Berryman Darlene E, Puri Vishwajeet, Lee Kevin Y, Jorgensen Jens O L
Abstract excerpt
The ability of growth hormone (GH) to induce adipose tissue lipolysis has been known for over five decades; however, the molecular mechanisms that mediate this effect and the ability of GH to inhibit insulin-stimulated glucose uptake have scarcely been documented. In this same time frame, our understanding of adipose tissue has evolved to reveal a complex structure with distinct types of adipocyte, depot-specific...
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