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Article

A CTG Clade Candida Yeast Genetically Engineered for the Genotype-Phenotype Characterization of Azole Antifungal Resistance in Human-Pathogenic Yeasts.

Antimicrobial agents and chemotherapy - 1 Jan 2018

Accoceberry Isabelle, Rougeron Amandine, Biteau Nicolas, Chevrel Pauline, Fitton-Ouhabi Valérie, Noël Thierry

Abstract excerpt

A strain of the opportunistic pathogenic yeast Candida lusitaniae was genetically modified for use as a cellular model for assessing by allele replacement the impact of lanosterol C14α-demethylase ERG11 mutations on azole resistance. Candida lusitaniae was chosen because it is susceptible to azole antifungals, it belongs to the CTG clade of yeast, which includes most of the Candida species pathogenic for humans,...

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Source

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Identifiers

PMID: 29038279
DOI: 10.1128/AAC.01483-17
PMCID: PMC5740319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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