Article
Undifferentiated carcinoma of the pancreas: analysis of intermediate filament profile and Ki-ras mutations provides evidence of a ductal origin.
The Journal of pathology - 1 May 1998
Hoorens A, Prenzel K, Lemoine N R, Klöppel G
Abstract excerpt
Undifferentiated carcinomas and osteoclast-like giant cell tumours of the pancreas commonly contain foci of neoplastic ductal glands. To test the hypothesis that undifferentiated carcinomas and osteoclast-like giant cell tumours have a ductal origin, the immunocytochemical cytokeratin pattern and...
Topics
- Adenocarcinoma
- Adult
- Aged
- Aged, 80 and over
- Carcinoma
- Female
- Genes, ras
- Giant Cell Tumors
- Humans
- Immunoenzyme Techniques
- Intermediate Filaments
- Keratins
- Male
- Middle Aged
- Mutation
- Neoplasm Proteins
- Pancreatic Neoplasms
- Polymorphism, Restriction Fragment Length
