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Article

Undifferentiated carcinoma of the pancreas: analysis of intermediate filament profile and Ki-ras mutations provides evidence of a ductal origin.

The Journal of pathology - 1 May 1998

Hoorens A, Prenzel K, Lemoine N R, Klöppel G

Abstract excerpt

Undifferentiated carcinomas and osteoclast-like giant cell tumours of the pancreas commonly contain foci of neoplastic ductal glands. To test the hypothesis that undifferentiated carcinomas and osteoclast-like giant cell tumours have a ductal origin, the immunocytochemical cytokeratin pattern and the frequency and type of Ki-ras mutations at colon 12 were studied in a series of 17 undifferentiated carcinomas and...

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Source

Identifiers

PMID: 9713360
DOI: 10.1002/(SICI)1096-9896(199805)185:1<53::AID-PATH45>3.0.CO;2-F

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