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Article

Characterization of the motility of monomeric kinesin-5/Cin8.

Biochemical and biophysical research communications - 28 May 2021

Yamagishi Masahiko, Maruyama Yohei, Sugawa Mitsuhiro, Yajima Junichiro

Abstract excerpt

Cin8, the Saccharomyces cerevisiae kinesin-5, has an essential role in mitosis. In in vitro motility assays, tetrameric and dimeric Cin8 constructs showed bidirectional motility in response to ionic strength or Cin8 motor density. However, whether property-switching directionality is present in a monomeric form of Cin8 is unknown. Here we engineered monomeric Cin8 constructs with and without the Cin8-specific ∼99...

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Identifiers

PMID: 33845395
DOI: 10.1016/j.bbrc.2021.03.134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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