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Article

Low paraoxonase activity in type II diabetes mellitus complicated by retinopathy.

Clinical science (London, England : 1979) - 1 Mar 2000

Mackness B, Durrington P N, Abuashia B, Boulton A J, Mackness M I

Abstract excerpt

Human serum paraoxonase 1 (PON1) is located on high-density lipoprotein and has been implicated in the detoxification of organophosphates, and possibly in the prevention of lipid peroxidation of low-density lipoprotein. PON1 has two genetic polymorphisms, both due to amino acid substitutions: one involving glutamine (Q genotype) and arginine (R genotype) at position 192, and the other involving leucine (L...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10677395

Genes

PON1
PON2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Low paraoxonase activity in type II diabetes mellitus complicated by retinopathy.PMID 10677395Read ↗

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