Article
Paraoxonase 1 gene polymorphisms and enzyme activities in diabetes mellitus.
Physiological research - 1 Jan 2008
Flekac M, Skrha J, Žídková K, Lacinová Z, Hilgertová J
Abstract excerpt
Paraoxonase 1 (PON1), an antioxidant enzyme closely associated with HDL (high-density lipoproteins), preserves LDL (low-density lipoproteins) against oxidation. Less protection may be therefore supposed by decreased PON1 activity. This study was undertaken to investigate the association of PON1 gene polymorphisms with diabetic angiopathy and to evaluate the relationship of these polymorphisms with PON1 activity....
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