Using the optimal receiver operating characteristic curve to design a predictive genetic test, exemplified with type 2 diabetes.

doi:10.1016/j.ajhg.2007.12.025

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Article

Using the optimal receiver operating characteristic curve to design a predictive genetic test, exemplified with type 2 diabetes.

American journal of human genetics - 1 Mar 2008

Lu Qing, Elston Robert C

Abstract excerpt

Current extensive genetic research into common complex diseases, especially with the completion of genome-wide association studies, is bringing to light many novel genetic risk loci. These new discoveries, along with previously known genetic risk variants, offer an important opportunity for researchers to improve health care. We describe a method of quick evaluation of these new findings for potential clinical...

Topics

Area Under Curve
Data Interpretation, Statistical
Diabetes Mellitus, Type 2
Genetic Diseases, Inborn
Genetic Predisposition to Disease
Genetic Techniques
Humans
Predictive Value of Tests
ROC Curve
Sensitivity and Specificity

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Identifiers

PMID: 18319073
DOI: 10.1016/j.ajhg.2007.12.025
PMCID: PMC2664997

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