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Article

Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy

1 Aug 1998

Abstract excerpt

Spinal and bulbar muscular atrophy (SBMA) is an X-linked motor neuronopathy caused by the expansion of an unstable CAG repeat in the coding region of the androgen receptor (AR) gene. To study AR protein expression in normal and SBMA individuals, we used several antibodies that recognize AR protein, and analyzed neural and nonneural tissues by immunohistochemistry and western blotting. Both the normal and the...

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Genetic Neurodegenerative Diseases
Neurogenetic and Muscular Disorders Research
RNA Research and Splicing

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 9708548
DOI: 10.1002/ana.410440216

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