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Article

Differential expression of genes involved in the degeneration and regeneration pathways in mouse models for muscular dystrophies.

Neuromolecular medicine - 1 Mar 2012

Onofre-Oliveira P C G, Santos A L F, Martins P M, Ayub-Guerrieri D, Vainzof M

Abstract excerpt

The genetically determined muscular dystrophies are caused by mutations in genes coding for muscle proteins. Differences in the phenotypes are mainly the age of onset and velocity of progression. Muscle weakness is the consequence of myofiber degeneration due to an imbalance between successive cycles of degeneration/regeneration. While muscle fibers are lost, a replacement of the degraded muscle fibers by adipose...

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PMID: 22362587
DOI: 10.1007/s12017-012-8172-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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