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Article

G-CSF supports long-term muscle regeneration in mouse models of muscular dystrophy

13 Apr 2015

Abstract excerpt

Duchenne muscular dystrophy (DMD) is a chronic and life-threatening disease that is initially supported by muscle regeneration but eventually shows satellite cell exhaustion and muscular dysfunction. The life-long maintenance of skeletal muscle homoeostasis requires the satellite stem cell pool to be preserved. Asymmetric cell division plays a pivotal role in the maintenance of the satellite cell pool. Here we...

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PMID: 25865621
DOI: 10.1038/ncomms7745

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