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Article

DNA sequence determinant for FIp-induced DNA bending.

Molecular microbiology - 1 Jul 1998

Luetke K H, Sadowski P D

Abstract excerpt

The Flp site-specific recombinase from Saccharomyces cerevisiae induces DNA bending upon interaction with the Flp recognition target (FRT) site. The minimal FRT site comprises the inverted a and b binding elements, which flank a central 8 bp core region. The DNA bend in a complex of two Flp monomers bound to the FRT site is located in the middle of the core region. When the central AT basepair was replaced with a...

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PMID: 9701814
DOI: 10.1046/j.1365-2958.1998.00922.x

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