Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Physical and enzymological interaction of Bacillus subtilis proteins required for de novo pyridoxal 5'-phosphate biosynthesis.

Journal of bacteriology - 1 Feb 2004

Belitsky Boris R

Abstract excerpt

Bacillus subtilis synthesizes pyridoxal 5'-phosphate, the active form of vitamin B(6), by a poorly characterized pathway involving the yaaD and yaaE genes. The pdxS (yaaD) mutant was confirmed to be a strict B(6) auxotroph, but the pdxT (yaaE) mutant turned out to be a conditional auxotroph depending on the availability of ammonium in the growth medium. The PdxS and PdxT proteins copurified during affinity...

Topics

Anthranilate Synthase
Bacillus subtilis
Bacterial Proteins
Base Sequence
Molecular Sequence Data
Mutation
Nitrogenous Group Transferases
Pyridoxal Phosphate

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 14762015
DOI: 10.1128/JB.186.4.1191-1196.2004
PMCID: PMC344226

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Physical and enzymological interaction of Bacillus subtilis proteins required for de novo pyridoxal 5'-phosphate biosynthesis.PMID 14762015Read ↗

A Bacillus subtilis ΔpdxT mutant suppresses vitamin B6 limitation by acquiring mutations enhancing pdxS gene dosage and ammonium assimilation.Semantic proximity Read ↗

Metabolic relationships between pyridoxine (vitamin B6) and serine biosynthesis in Escherichia coli K-12.Semantic proximity Read ↗

Mutational analyses reveal PLP-independent functions at PipY, the cyanobacterial paradigm for pyridoxal-phosphate binding proteins.Semantic proximity Read ↗

Mutational analyses reveal PLP-independent functions at PipY, the cyanobacterial paradigm for pyridoxal-phosphate binding proteinsSemantic proximity Read ↗

Adenylosuccinate lyase of Bacillus subtilis regulates the activity of the glutamyl-tRNA synthetase.Semantic proximity Read ↗

Involvement of the gapA- and epd (gapB)-encoded dehydrogenases in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12.Semantic proximity Read ↗

Cloning, expression, and functional interactions of the amidotransferase domain of mammalian CAD carbamyl phosphate synthetase.Semantic proximity Read ↗

Functional genomic, biochemical, and genetic characterization of the Salmonella pduO gene, an ATP:cob(I)alamin adenosyltransferase gene.Semantic proximity Read ↗

Crystal structures capture three states in the catalytic cycle of a pyridoxal phosphate (PLP) synthase.Semantic proximity Read ↗

The PduX enzyme of Salmonella enterica is an L-threonine kinase used for coenzyme B12 synthesis.Semantic proximity Read ↗

Enzymatic activities and functional interdependencies of Bacillus subtilis lipoteichoic acid synthesis enzymes.Semantic proximity Read ↗

Purification and enzymatic characterization of PgcM: a beta-phosphoglucomutase and glucose-1-phosphate phosphodismutase of Bacillus subtilis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.