Article
Bacterial lipopolysaccharide contamination of commercial collagen preparations may mediate dendritic cell maturation in culture.
Journal of immunological methods - 1 May 1998
Suri R M, Austyn J M
Abstract excerpt
Dendritic cells (DC) are potent antigen presenting cells, which are responsible for the initiation of naive T and T-dependent immune responses. The present studies were based upon recent reports that commercial collagen I preparations induce the maturation of human DC in vitro. We show that human blood monocyte-derived (GM-CSF and IL-4 cultured) DC pulsed on collagen I-coated plates undergo a dose-dependent...
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