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Article

Inhibition of in vitro differentiation of human monocytes to macrophages by lipopolysaccharides (LPS): phenotypic and functional analysis.

International immunology - 1 Mar 1991

Brugger W, Reinhardt D, Galanos C, Andreesen R

Abstract excerpt

Blood monocytes (MO) undergo maturation into macrophages (MAC) upon migration from the capillary bed to tissue sites of inflammation where they are exposed to environmental signals. Functional competence and phenotype heterogeneity is the result of both differentiation-inducing and -activating ev...

Topics

Cell Differentiation
Humans
In Vitro Techniques
Interferons
Interleukin-6
Lipopolysaccharides
Macrophages
Monocytes
Phenotype
Tumor Necrosis Factor-alpha

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1710926
DOI: 10.1093/intimm/3.3.221

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1710926-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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