Article
Tumor suppressor mutations in mice: the next generation.
Current opinion in genetics & development - 1 Jun 1998
McClatchey A I, Jacks T
Abstract excerpt
Mouse strains carrying tumor suppressor mutations genetically mimic familial forms of human cancer. New tumor suppressors have and will be identified and mutated in the mouse; however, it is clear that future investigation will focus on a new generation of experiments aimed at improving existing...
Topics
- Animals
- Disease Models, Animal
- Forecasting
- Genes, Tumor Suppressor
- Humans
- Mice
- Mutation
- Neoplasms, Experimental
- Research