Lack of association between carotid intima-media thickness and paraoxonase gene polymorphism in non-insulin dependent diabetes mellitus.

doi:10.1016/s0021-9150(98)00031-8

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Article

Lack of association between carotid intima-media thickness and paraoxonase gene polymorphism in non-insulin dependent diabetes mellitus.

Atherosclerosis - 1 Jun 1998

Cao H, Girard-Globa A, Serusclat A, Bernard S, Bondon P, Picard S, Berthezene F, Moulin P

Abstract excerpt

Paraoxonase (PON) is an HDL-bound enzyme capable of hydrolyzing lipid peroxides and believed to be in part responsible for the protective effect of HDL against LDL oxidation. Its activity is mainly determined by a gene polymorphism of the PON 1 gene (Glu-Arg 192). Low activity has been related to...

Topics

Age Factors
Alleles
Aryldialkylphosphatase
Blood Pressure
Carotid Arteries
Diabetes Mellitus, Type 2
Esterases
Female
Humans
Male
Middle Aged
Polymorphism, Genetic
Regression Analysis
Tunica Intima
Tunica Media

Source

Open in PubMed

Identifiers

PMID: 9690920
DOI: 10.1016/s0021-9150(98)00031-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9690920-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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