Article
Relation between microsatellite instability and N-ras mutation and duration of disease free survival in patients with acute leukemia.
Cancer - 1 Aug 1998
Tanosaki S, Inokuchi K, Shimada T, Dan K
Abstract excerpt
BACKGROUND: Microsatellite instability (MIN) appears to be a novel molecular mechanism in carcinogenesis and is believed to reflect multiple replication errors. The authors analyzed MIN in de novo acute leukemia and its association with expression of the human MSH3 (hMSH3) gene and point mutations of the N-ras gene. The relation between MIN and disease free survival also was examined. METHODS: The authors studied...
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