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Article

Microsatellite instability during the progression of acute myelocytic leukaemia

1 Jul 1997

Abstract excerpt

We studied microsatellite instability (MSI) at the onset and during progression of 17 individuals with acute myelocytic leukaemia (AML). These included two cases of MO, eight with M1 and seven with M4, according to the FAB classification. The DNA from diagnostic, remission and relapsed stages of their disease was analysed at 69 loci. Two MSI were found in the diagnostic and remission phase paired samples (12%),...

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PMID: 9233589
DOI: 10.1046/j.1365-2141.1997.1672985.x

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