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Genetic studies of polymorphisms in ten non-insulin-dependent diabetes mellitus candidate genes in Tamil Indians from Pondichery.

Diabetes & metabolism - 1 Jun 1998

Leprêtre F, Vionnet N, Budhan S, Dina C, Powell K L, Génin E, Das A K, Nallam V, Passa P, Froguel P

Abstract excerpt

We report a study of 10 candidate genes presumably involved in diabetes or insulin resistance or obesity among Pondicherian Tamil Indians, an isolated population with a high prevalence of diabetes. Forty-nine families with at least two affected patients in the sibship (567 individuals) were selected and tested by PCR-RFLP techniques for reported mutations in 10 diabetes or obesity candidate genes: glucagon...

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PMID: 9690058

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