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Article

Zf9, a Kruppel-like transcription factor up-regulated <i>in vivo</i> during early hepatic fibrosis

4 Aug 1998

Abstract excerpt

Wound repair in the liver induces altered gene expression in stellate cells (resident mesenchymal cells) in a process known as "activation." A zinc finger transcription factor cDNA, zf9, was cloned from rat stellate cells activated in vivo. Zf9 expression and biosynthesis are increased markedly in activated cells in vivo compared with cells from normal rats ("quiescent" cells). The factor is localized to the...

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PMID: 9689109
DOI: 10.1073/pnas.95.16.9500

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